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Drug war: On use of antibiotics and antimicrobial resistance

Drug war: On use of antibiotics and antimicrobial resistance
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Drug war: On use of antibiotics and antimicrobial resistance

  • The ‘First Multicentric Point Prevalence Survey of Antibiotic Use at 20 NAC-NET Sites India 2021-22’ reveals alarming statistics.
  • It was conducted by the National Centre for Disease Control under the Health Ministry

Survey Findings

  • Over 70% of patients in tertiary-care hospitals across 15 States and two UTs were prescribed antibiotics.
  • More than 50% of prescribed antibiotics have the potential to cause Antimicrobial Resistance (AMR).
  • 55% of patients received antibiotics as prophylaxis or as a preventive, while only 45% were prescribed antibiotics for actual infection treatment.
    • A mere 6% of patients received antibiotics after identifying the specific bacteria causing the infection.

Antimicrobial Resistance (AMR) Crisis

  • AMR occurs when pathogens evolve, rendering themselves resistant to drugs and unresponsive to antimicrobial treatment.
  • Unsound medical and animal husbandry practices contribute to the escalating crisis.
  • The misuse and overuse of antimicrobials cause the development of drug-resistant pathogens that in turn pose great risk to life and exacerbate morbidity.
  • WHO estimates that bacterial AMR directly caused 1.27 million global deaths in 2019 and contributed to 4.95 million deaths.
  • AMR compromises the effectiveness of medical procedures like surgery, caesarean sections and cancer chemotherapy.

Way Forward

  • Specialists emphasise the need for rational antibiotic prescriptions and restrictions on drug use to promote growth in animals and plants.
  • Urgent measures are required to develop new drug candidates, and more equitable access to them to address the antibiotic research and development pipeline crisis.
  • Both doctors and the government play crucial roles in regulating drug use, especially the government.
  • Patients' expectations of immediate relief should also be tempered with an understanding of the complexities of medical science.
  • Strict regulation of antimicrobial use and increased funding for antibiotic research are essential in the battle against AMR.

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