| Event | 14th World Down Syndrome Day Conference |
| Date (Conference) | 21 March 2025 |
| Location (Conference) | United Nations Headquarters, New York |
| Organizer | Down Syndrome International network |
| Additional Events | UN Events in Geneva |
| Date (Geneva Events) | 20-22 March 2025 |
| Location (Geneva Events) | United Nations, Geneva |
| Activities | Panel discussions, awareness campaigns, community engagement programs |
| Down Syndrome Definition | Genetic condition due to extra partial or whole copy of chromosome 21 |
| Impact of Down Syndrome | Physical, cognitive, and developmental challenges; variable effects on learning and health |
| Cause of Down Syndrome | Exact cause unknown; occurs globally |
| Incidence Rate | 1 in 1,000 to 1 in 1,100 live births |
| Annual Births with DS | Approximately 3,000 to 5,000 children |
| World Down Syndrome Day | Established by UN Resolution A/RES/66/149 in December 2011 |
| First Observed | 2012 |
| Main Objectives | Promote awareness, inclusion, healthcare, education, employment, and policy advocacy for DS |
| Global Participation | UN Member States, organizations, civil society, NGOs, private sector |
| Support Needs for DS Individuals | Education, healthcare, social inclusion, employment |
| Family Role | Crucial for support and care; need resources, financial aid, and counseling |
| Support System Gaps | Lack of necessary support and adequate policies in many countries |
| Government Responsibilities | Ensure healthcare, inclusive education, employment opportunities, legal protection for DS |